Human Insulin Does Not Increase Bladder Cancer Risk

Human Insulin Does Not Increase Bladder Cancer Risk

BACKGROUND Whether human insulin can induce bladder cancer is rarely studied. METHODS The reimbursement databases of all Taiwanese diabetic patients from 1996 to 2009 were retrieved from the National Health Insurance. An entry date was set at 1 January 2004 and a total of 785,234 patients with type 2 diabetes were followed up for bladder cancer incidence until the end of 2009. Users of piogli...

Pioglitazone does not increase the risk of type II diabetes in patients with bladder cancer: A retrospective study

The aim of the retrospective study was to analyze the effect of pioglitazone on the expression of tumor tissue inflammation factor interleukin (IL)-8, macrophage colony-stimulating factor (M-CSF) and vascular endothelial growth factor (VEGF) of type II diabetes in bladder cancer patients. In addition, whether there was a correlation between pioglitazone and the occurrence of male bladder cancer...

Does Insulin Glargine Increase the Risk of Cancer Compared With Other Basal Insulins?

OBJECTIVE To explore in France the relationship between insulin glargine use and overall and specific cancer risks in type 2 diabetic patients compared with other basal insulins. RESEARCH DESIGN AND METHODS Data were extracted from French health insurance information system (Système National d'Information Inter-Régimes de l'Assurance Maladie) linked with data from the French Hospital Discharg...

Radical Prostatectomy Does Not Increase the Risk of Inguinal Hernia

Nitrate Intake Does Not Influence Bladder Cancer Risk: The Netherlands Cohort Study

OBJECTIVES N-nitroso compounds, endogenously formed from nitrate-derived nitrite, are suspected to be important bladder carcinogens. However, the association between nitrate exposure from food or drinking water and bladder cancer has not been substantially investigated in epidemiologic studies. METHODS We evaluated the associations between nitrate exposure and bladder cancer in the Netherland...